Biological Risks
Biological risks encompass the dangerous modification of pathogens and unethical manipulation of genetic material, potentially leading to unforeseen biohazardous outcomes.
ENTITY
3 - Other
INTENT
2 - Unintentional
TIMING
3 - Other
Risk ID
mit1437
Domain lineage
4. Malicious Actors & Misuse
4.2 > Cyberattacks, weapon development or use, and mass harm
Mitigation strategy
1. Implement a stringent, mandatory, and pre-emptive administrative control layer through the institutionalization of an independent Dual-Use Research of Concern (DURC) and ethics review process to vet all proposed research involving the modification of pathogens or novel manipulation of genetic material, thereby reducing the *likelihood* of dangerous or unethical work proceeding. 2. Mandate the use of appropriate, risk-assessment-derived Engineering Controls, specifically certified Biological Safety Cabinets (BSCs) and specialized containment facilities (up to the required Biosafety Level - BSL), to physically isolate the biohazard and prevent the *unintentional release* or exposure of workers, community, and the environment. 3. Establish robust, continually evaluated Administrative Controls and practices, including required proficiency training, clear Standard Operating Procedures (SOPs), stringent access and inventory control for agents (biosecurity), and a comprehensive incident reporting and investigation system to manage residual risks and ensure a positive culture of safety.